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Adipotide

Metabolic

Also known as: FTPP, CKGGRAKDC-GG-D(KLAKLAK)2

๐Ÿงช Reconstitution Guide for Adipotide

Dose calculator, BAC water volumes, and syringe unit tables.

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๐Ÿ’ฐ Vendor Pricing Comparison

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Overview

Adipotide (FTPP, fat-targeting proapoptotic peptide) is a synthetic chimeric peptide designed to selectively ablate the blood supply feeding white adipose tissue. Preclinical studies in non-human primates demonstrated rapid, significant weight loss through targeted apoptosis of adipose vasculature.

Mechanism of Action

Adipotide consists of two functional domains: a fat-homing sequence (CKGGRAKDC) that binds prohibitin on the luminal surface of adipose blood vessels, and a proapoptotic D(KLAKLAK)โ‚‚ sequence that disrupts mitochondrial membranes, selectively inducing apoptosis in vasculature supplying white fat depots.

Common Research Uses

  • Targeted fat ablation research
  • Obesity research
  • Angiogenesis-targeted therapy studies
  • Adipose tissue biology research

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