Vardenafil

Overview

Vardenafil is the sulfonamide resulting from formal condensation of the sulfo group of 4-ethoxy-3-(5-methyl-7-propylimidazo[5,1-f][1,2,4]triazin-4(1H)-one-2-yl)benzenesulfonic acid and the secondary amino group of 4-ethylpiperazine. It has a role as a vasodilator agent and an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor. It is a N-alkylpiperazine, an imidazotriazine and a N-sulfonylpiperazine.

Source: ChEBI (CC BY 4.0), via PubChem.

PubChem record

CID 135400189 · Vardenafil

Molecular formula · weight

C23H32N6O4S · 488.6 g/mol

PubMed papers naming it (title/abstract)

1,236 search: “Vardenafil”

Registered clinical studies (ClinicalTrials.gov)

83 intervention: “Vardenafil”

Reference facts checked 2026-11-09. Counts are search results, not a judgement of the evidence.