Tropisetron

Overview

Tropisetron is an indolyl carboxylate ester obtained by formal condensation of the carboxy group of indole-3-carboxylic acid with the hydroxy group of tropine. It has a role as a trypanocidal drug, a nicotinic acetylcholine receptor agonist, a serotonergic antagonist, an immunomodulator, an antiemetic, a neuroprotective agent, an anti-inflammatory agent and an apoptosis inhibitor. It is an azabicycloalkane, an indolyl carboxylate ester and a tertiary amino compound. It is functionally related to a tropine and an indole-3-carboxylic acid. It is a conjugate base of a tropisetron(1+).

Source: ChEBI (CC BY 4.0), via PubChem.

PubChem record

CID 656665 · Tropisetron

Molecular formula · weight

C17H20N2O2 · 284.35 g/mol

PubMed papers naming it (title/abstract)

1,039 search: “Tropisetron”

Registered clinical studies (ClinicalTrials.gov)

47 intervention: “Tropisetron”

Reference facts checked 2026-11-09. Counts are search results, not a judgement of the evidence.