Sildenafil
Sexual HealthPrescription drug (research listing)Overview
Sildenafil is a pyrazolo[4,3-d]pyrimidin-7-one having a methyl substituent at the 1-position, a propyl substituent at the 3-position and a 2-ethoxy-5-[(4-methylpiperazin-1-yl)sulfonyl]phenyl group at the 5-position. It has a role as a vasodilator agent and an EC 3.1.4.35 (3',5'-cyclic-GMP phosphodiesterase) inhibitor. It is a member of piperazines, a sulfonamide and a pyrazolopyrimidine.
Source: ChEBI (CC BY 4.0), via PubChem.
- PubChem record
- CID 135398744 · Sildenafil
- Molecular formula · weight
- C22H30N6O4S · 474.6 g/mol
- PubMed papers naming it (title/abstract)
- 8,394 search: “Sildenafil”
- Registered clinical studies (ClinicalTrials.gov)
- 494 intervention: “Sildenafil”
Reference facts checked 2026-11-09. Counts are search results, not a judgement of the evidence.
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Blends containing Sildenafil
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