PNC-27
ImmuneAlso known as: p53-MDM2 inhibitor peptide, HDM-2-binding peptide
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Overview
PNC-27 is a synthetic peptide derived from the p53 protein sequence and studied in anticancer laboratory research. It is typically described as a p53-derived membrane-active peptide investigated in tumor-cell models.
Mechanism of Action
PNC-27 has been studied for binding to HDM-2/MDM2 and for forming membrane-associated complexes in cells expressing membrane HDM-2. Experimental work examines resulting membrane disruption and selective cytotoxicity markers in cancer-cell systems.
Common Research Uses
- anticancer peptide research
- p53-derived peptide studies
- MDM2 interaction assays
- tumor-cell membrane research
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