Liraglutide

Overview

Liraglutide is a lipopeptide that is an analogue of human GLP-1 in which the lysine residue at position 27 is replaced by arginine and a hexadecanoyl group attached to the remaining lysine via a glutamic acid spacer. Used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It has a role as a neuroprotective agent and a glucagon-like peptide-1 receptor agonist. It is a polypeptide and a lipopeptide.

Source: ChEBI (CC BY 4.0), via PubChem.

PubChem record

CID 16134956 · Liraglutide

Molecular formula · weight

C172H265N43O51 · 3751 g/mol

PubMed papers naming it (title/abstract)

5,733 search: “Liraglutide”

Registered clinical studies (ClinicalTrials.gov)

520 intervention: “Liraglutide”

Reference facts checked 2026-11-09. Counts are search results, not a judgement of the evidence.