← Peptide Index/GHRP-6

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GHRP-6

GH Secretagogue

Also known as: GHRP6, Growth Hormone Releasing Peptide-6

🧪 Reconstitution Guide for GHRP-6

Dose calculator, BAC water volumes, and syringe unit tables.

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💰 Vendor Pricing Comparison

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Overview

GHRP-6 (Growth Hormone-Releasing Peptide 6) is a synthetic hexapeptide ghrelin mimetic that potently stimulates GH secretion. It is the prototypical first-generation GHRP, notable for producing large GH pulses alongside pronounced appetite stimulation via hypothalamic ghrelin pathway activation.

Mechanism of Action

GHRP-6 activates the ghrelin receptor (GHSR-1a) in both the pituitary and hypothalamus, stimulating GH release while also activating appetite-promoting NPY/AgRP neurons. It produces larger GH pulses than ipamorelin but is associated with greater hunger stimulation, elevated cortisol, and prolactin secretion.