Dihexa
CognitiveAlso known as: PNB-0408, N-hexanoic-Tyr-Ile-(6) aminohexanoic amide
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Overview
Dihexa is a synthetic angiotensin IV-derived peptide analog studied in neurobiology and cognition-related research. It was designed for improved stability and blood-brain barrier penetration relative to parent angiotensin-derived fragments.
Mechanism of Action
Dihexa is studied for modulation of hepatocyte growth factor/c-Met signaling and synaptogenic pathways. Research models examine effects on dendritic spine formation, synaptic connectivity markers, and learning-associated signaling cascades.
Common Research Uses
- synaptogenesis research
- cognitive model studies
- HGF/c-Met pathway assays
- neuroplasticity research
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