CMS-121

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Overview

CMS-121 is a quinolone derivative and an orally active acetyl-CoA carboxylase 1 (ACC1) inhibitor. CMS-121 protects HT22 cells against ischemia and oxidative damage. CMS-121 has strong neuroprotective, anti-inflammatory, antioxidative and renoprotective activities.

Source: ChEBI (CC BY 4.0), via PubChem.

PubChem record: CID 135741221 · Cms-121
Molecular formula · weight: C20H19NO3 · 321.4 g/mol
PubMed papers naming it (title/abstract): 13 search: “CMS121”
Registered clinical studies (ClinicalTrials.gov): 1 intervention: “CMS121”

Reference facts checked 2026-11-09. Counts are search results, not a judgement of the evidence.

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