CJC-1295 No DAC

Overview

CJC-1295 No DAC (also known as Modified GRF 1-29) is a GHRH analogue incorporating four stabilizing amino acid substitutions without the albumin-binding DAC modification. With a half-life of approximately 30 minutes, it produces discrete, pulsatile GH release and is most commonly used in combination with a GHRP for synergistic GH secretion.

Mechanism of Action

CJC-1295 No DAC stimulates GHRH receptors on pituitary somatotrophs, producing a strong and natural-pattern GH pulse when co-administered with a GHRP (such as ipamorelin or GHRP-2). The shorter half-life versus the DAC form more closely mimics physiological GH pulsatility.

Common Research Uses

• Pulsatile GH optimization research
• Combined GHRH/GHRP protocols
• Anti-aging and recovery research
• Sleep and body composition studies
• GH axis research

Vendors That Carry CJC-1295 No DAC