Avanafil

Sexual HealthPrescription drug (research listing)

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Overview

Avanafil is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 4-[(3-chloro-4-methoxybenzyl)amino]-2-[(2S)-2-(hydroxymethyl)pyrrolidin-1-yl]pyrimidine-5-carboxylic acid with the amino group of pyrimidin-2-ylmethylamine. It has a role as a vasodilator agent and an EC 3.1.4.* (phosphoric diester hydrolase) inhibitor. It is a monocarboxylic acid amide, an organochlorine compound, a member of pyrimidines, a member of prolinols and an aromatic amide.

Source: ChEBI (CC BY 4.0), via PubChem.

PubChem record: CID 9869929 · Avanafil
Molecular formula · weight: C23H26ClN7O3 · 483.9 g/mol
PubMed papers naming it (title/abstract): 196 search: “Avanafil”
Registered clinical studies (ClinicalTrials.gov): 24 intervention: “Avanafil”

Reference facts checked 2026-11-09. Counts are search results, not a judgement of the evidence.

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