ACE-031
RecoveryAlso known as: ACVR2B, ActRIIB-Fc
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Overview
ACE-031 is a recombinant soluble activin receptor type IIB fusion protein used in muscle biology research. It functions as a ligand trap for myostatin-related TGF-beta family signaling proteins in experimental systems.
Mechanism of Action
ACE-031 binds selected ActRIIB ligands such as myostatin and activins, reducing their availability for cell-surface receptor signaling. This decoy-receptor mechanism is studied for downstream effects on SMAD-mediated pathways involved in muscle growth regulation.
Common Research Uses
- myostatin pathway studies
- muscle mass research models
- ActRIIB ligand binding assays
- recovery biology research
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